With various factors due to aging, the level of hyaluronic acid (HA) in the upper skin decreases and as a result the skin ages and becomes thinner; skin's moisture decreases, elasticity and tension disappear. When the hyaluronic acid creams are applied to the skin, the moisture gradient of the skin increases; a thin film layer is formed on the skin and the skin is softened; flexibility and restructuring of the skin is provided. The use of HA was approved by the American Food and Drug Administration (FDA) in 2003


The main functions and properties of hyaluronic acid are as follows:


- It acts as cement between cells and connects the cells together


- It acts as a cushion or pillow against strokes and shocks.


- It provides lubricity and absorbs shock. It helps all the cells in the connective tissue to slide on each other in flexing and curling.

The softness, moisture and tightness of the baby's skin depends on the amniotic fluid that the baby swims in the womb is very rich in terms of hyaluronic acid.


- The water-holding capacity of hyaluronic acid for cells that do not supply blood directly, such as cartilage cells; it helps to carry out important biological functions such as supplying nutrients and removing wastes from cells. It also plays a role in the growth, development and repair of subcutaneous tissues.


It is suitable for the production of new, biocompatible and biodegradable polymers which may be the main component of tissue engineering and drug delivery systems.


What is hyaluronic acid filling material?


This filling material, which is in the form of a clear, transparent gel, is the production of hyaluronic acid which is normally found in the body by biotechnological methods and is given to the body as a supplement. Hyaluronic acid is normally a polysaccharide connective tissue element found in connective tissues, collagen fibers of all living organisms (plants, animals and humans) and gives fullness, brightness and smoothness to the skin. The disappearance of hyaluronic acid in the skin structure over time is one of the most important factors in aging of the skin and causes the skin to fade, wrinkle, and fine fine lines. By injecting this filling material into the skin, the brightness, fullness and elasticity of the skin are provided.


In which areas is this filling material applied?


For polishing up fine lines


For the removal of nasolabial depressions extending from both nasal wings to the rim


For clarification of lip curl and thickening of lip


For fine wrinkles around the lips and lines extending down the corners of the mouth,


It is used in lines on neck, dorsum of the hand and decollete.


Where is the hyaluronic acid treatment made, how long does it take?


Local anesthesia is rarely used in these injections, which can be easily performed in the examination conditions. After cleansing the skin with alcohol or other antiseptic substance, filling material is injected into the skin with its very fine tipped special injectors to fill wrinkles.


The procedure is performed in about 15-20 minutes without any side effects except slight swelling and redness at the injection site.


How often should hyaluronic acid filling material be applied?


This filling material is excreted with slow absorption from the body. This takes about 6 months. Normally, a much smaller amount of filling material is slowly cleared from the body than the daily hyaluronic acid metabolism in the body removes. Therefore, it is a process that needs to be renewed every 6 months. However, this time may vary depending on the area being treated, the structure of the skin, anatomy and lifestyle.


What are the side effects of the procedure?


Since it is a naturally occurring substance in the body, it is not possible to produce an allergic reaction. It is FDA approved and widely used in America. Very mild swelling and redness may occur after the procedure. This swelling spontaneously resolves within 48 hours. Any irregularities that may occur or areas that need to be supplied can be corrected by re-injection of the filling material 15 days after the procedure.


In which cases is hyaluronic acid filling material not applied?


During pregnancy and lactation, application should be avoided since there is not enough information about the subject. In addition, in cases of herpes infections around the lip, injection to this area should be postponed. It should not be applied in the areas of inflammation and allergic reactions.